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| Hailey Hailey Disease (Familial Benign Pemphigus) ： ウィキペディア英語版 |
Hailey–Hailey disease
Hailey–Hailey disease, or familial benign chronic pemphigus〔James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. ISBN 0-7216-2921-0.〕 or familial benign pemphigus〔Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.〕 was originally described by the Hailey brothers (Hugh Edward and William Howard) in 1939.〔H. Hailey, H. Hailey. Familial benign chronic pemphigus. Report of 13 cases in four generations of a family and report of 9 additional cases in 4 generations of a family. Archives of Dermatology and Syphilology, Chicago, 1939, 39: 679-685.〕 It is a genetic disorder that causes blisters to form on the skin. Sometimes known as Gougerot-Hailey-Hailey syndrome to acknowledge the contribution of Henri Gougerot in 1933.
== Classification ==
While the term pemphigus typically refers to "a rare group of blistering autoimmune diseases" affecting "the skin and mucous membranes", Hailey-Hailey disease is not an autoimmune disorder and there are no autoantibodies. According to Pemphigus Pemphigoid Foundation (IPPF), "familial benign chronic pemphigus, or Hailey-Hailey disease, is a different condition from Pemphigus".〔(【引用サイトリンク】url=http://www.pemphigus.org/research/clinically-speaking/pemphigus/ )〕
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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